Software Open Access

Generalized Multiscale Entropy Analysis

Published Feb. 2, 2019 · Version 1.0.0
Please include the standard citation for PhysioNet:

Pollard, T., Moody, B. E., Lehman, L., Gow, B., Fernandes, C., Xie, C., Johnson, A., Mark, R. G., & Heldt, T. (2026). PhysioNet as a global platform for biomedical research. Nature Health. https://doi.org/10.1038/s44360-026-00096-z. Available from: https://rdcu.be/faatM

The method of generalized multiscale entropy (GMSE) analysis is useful for investigating complexity in physiologic signals and other series that have correlations at multiple (time) scales. It represents a generalization of the original method of multiscale entropy analysis.

A tutorial about generalized multiscale entropy analysis is available in the tutorial directory. It discusses various methods for calculating a coarse-grained time series, and the impact of this choice on the multiscale entropy calculation. The results are illustrated using simulated data as well as real inter-beat interval data.

The software described in the tutorial in is gmse.c.


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