PhysioNet is a global platform for sharing biomedical and clinical data, software, machine-learning models, and educational resources. Funded by the US National Institutes of Health (NIH), it supports reproducible research through the publication of rigorously curated, de-identified data and related research tools.

Established in 1999, PhysioNet has grown from a repository of physiological waveforms into a community resource spanning biomedical research. Its mission is to make biomedical and clinical data freely available to the research community and to enable reproducible, data-driven research that improves human health.

PhysioNet is managed by the MIT Laboratory for Computational Physiology , with contributions from the global research community. Related research and educational activities in complex physiological signal analysis are also carried out by the Margret and H.A. Rey Institute for Nonlinear Dynamics at Beth Israel Deaconess Medical Center.

PhysioNet hosts hundreds of resources, including physiological signals, structured electronic health records, clinical text, imaging, curated annotations, open-source software, and machine-learning models. Most resources are openly available. Others require training, credentialing, and agreement to terms of use. The platform follows the FAIR principles—findability, accessibility, interoperability, and reusability—to support the long-term value and reuse of these resources.

PhysioNet serves more than 250,000 registered users from over 180 countries. Its resources have been referenced in more than 49,000 articles since 2001, supporting work in cardiology, critical care, medical informatics, artificial intelligence, and other fields.

PhysioNet also supports benchmarking, education, and collaboration. Research challenges organized by PhysioNet collaborators bring researchers together to address important unsolved problems. Its resources underpin courses, datathons, and training programs worldwide.

All resources published on PhysioNet undergo curation and review. We welcome contributions from the research community, including datasets, software, annotations, benchmarks, and educational materials. Please read our contributor guidelines before submitting your work.

PhysioNet traces its origins to the creation of the MIT-BIH Arrhythmia Database in the late 1970s, one of the earliest broadly shared benchmark datasets for evaluating arrhythmia detection algorithms. Together with other foundational ECG databases, it helped establish standards for transparent evaluation, shared test data, and objective comparison of biomedical signal-processing methods.

In 1999, Roger Mark and George Moody at MIT, together with Ary Goldberger at Beth Israel Deaconess Medical Center and Eugene Stanley at Boston University, founded the NIH Research Resource for Complex Physiologic Signals. At its founding, the resource unified PhysioBank, a repository of curated datasets; PhysioToolkit, open-source analysis software; and the PhysioNet web portal, which provided a shared environment for reproducible research. Over time these components became deeply intertwined, and in 2019 the distinctions between them were retired as the platform was consolidated under the single name PhysioNet.

What began as a small signal-processing archive has grown into a global platform supporting biomedical research across disciplines, from physiological signal processing and critical care to clinical informatics and translational AI. For more background, see: https://jclinic.mit.edu/physionet-at-25/

PhysioNet was originally established under the NIH National Center for Research Resources (NCRR). Current support comes from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), the National Heart, Lung, and Blood Institute (NHLBI), and the NIH Office of the Director under grant numbers U24EB037545 and R01EB030362.

If you use data or software from PhysioNet in a publication, please credit the author(s) when referencing it. You can find authors' names, and in many cases their publications introducing the data or software, on the project pages for their contributions. Please also include the two following citations for PhysioNet:

Pollard T, Moody BE, Lehman L, Gow B, Fernandes C, Xie C, Johnson A, Mark RG, Heldt T. PhysioNet as a Global Platform for Biomedical Research. Nature Health (2026). https://doi.org/10.1038/s44360-026-00096-z. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC13641116/

Goldberger AL, Amaral LAN, Glass L, Hausdorff JM, Ivanov PCh, Mark RG, Mietus JE, Moody GB, Peng C-K, Stanley HE. PhysioBank, PhysioToolkit, and PhysioNet: Components of a New Research Resource for Complex Physiologic Signals. Circulation 101(23):e215-e220 [Circulation Electronic Pages; http://circ.ahajournals.org/content/101/23/e215.full]; 2000 (June 13).

PhysioNet is maintained by researchers and engineers at the MIT Laboratory for Computational Physiology. To reach us, email contact@physionet.org.